HYALURON ACTIV PROCEDURE

DERMO-AESTHETIC AVENE INNOVATION

Avène introduces a pioneering skincare approach that transposes the latest advances in Aesthetic Dermatology to Dermo-Cosmetics.

Co-developed with aesthetic dermatologists, the HYALURON ACTIV PROCEDURE range can be used alone or alongside an aesthetic procedure¹ to enhance its results. The formulas combine key dermatological ingredients – recognised and used in aesthetic medicine – with pure, concentrated, and expertly crafted compositions.

At the heart of this innovative range is the Lifting Cream: a unique, high-performance formula with clinically proven results. Facial contours are lifted, cell performances are activated, and most remarkably, the skin looks 7 years younger².

(1) After re-epidermization
(2) Pharmaco-clinical study, on 42 women, 1 application/day of the product for 2 months.

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Clinically proven efficacy: Skin looks 7 years younger²

 

(2) Pharmaco-clinical study, on 42 women, 1 application/day of the product for 2 months.

*Pharmaco-clinical study, on 42 women, 1 application/day of the product for 2 months.

HYALURON ACTIV PROCEDURE - Lifting Cream

The Lifting Cream is formulated with three pure, concentrated actives recognised in aesthetic medicine. It delivers ultra-effective, multi-corrective anti-wrinkle action. With its creamy and enveloping texture, it penetrates easily into the skin to lift facial contours and activate cellular performance. Results: skin looks 7 years younger*, skin is smoother, firmer, and wrinkles are corrected.

*Pharmaco-clinical study, on 42 women, 1 application/day of the product for 2 months.

Discover the Lifting Cream

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CLINICALLY PROVEN RESULTS FOR VISIBLY YOUNGER-LOOKING SKIN

  1. -12%

    wrinkles³

  2. +47% Firmer skin³
  3. +42% Smoother skin³

(3) Clinical study, 44 subjects, 1 application per day, 2 months

A HIGH-PERFORMANCE FORMULA

Enriched with dermatological actives recognised in aesthetic medicine

  • Av_hyaluron_activ_procedure_active_ingredient_retinal

    0.1% Retinal

    3x more active than Retinol* and well tolerated, this is the most effective form of Vitamin A. It corrects the appearance of wrinkles.

     

    *External publication: J.H. Saurat & al., J Invest Dermatol, 1994; 102: 770-774. Clinical study on biopsies, 5 subjects, 1 application/day for 4 days.

  • Av_hyaluron_activ_procedure_active_ingredient_niacinamide

    2% Niacinamide

    Stimulates skin cells and extends their longevity** to fight the signs of ageing.

     

    ** In vitro test

  • Av_hyaluron_activ_procedure_active_ingredient_hyaluronic_acid

    Hyaluronic Acid

    Pure and of natural origin, it moisturises and enhances skin elasticity.
     

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    Rejuvenation proven by pioneering clinical studies

    Biological age: a breakthrough in dermo-cosmetics

    To evaluate the efficacy of the Lifting Cream, our researchers measured the skin’s biological age, its real age, reflecting the skin’s physiological condition. This is a more reliable indicator than chronological age, which simply reflects the number of years lived.
    By combining multiple biological markers, this method offers a far more precise assessment of skin cell vitality and function.
    The clinical study revealed a remarkable result: the skin looks 7 years younger².

    (2) Pharmaco-clinical study, on 42 women, 1 application/day of the product for 2 months.

    EXPERT TIP

    Use once or twice a week for the first two weeks, then gradually increase to once daily – preferably in the evening – depending on your skin’s tolerance to the product.

    HYALURON ACTIV PROCEDURE - Tightening Serum

    Used as a 14-day intensive treatment, this serum targets and corrects the five key signs of ageing: wrinkles, volume, firmness, radiance, and complexion1. Directly inspired by aesthetic dermatology practice, the hexapeptide-based formula is released at the last minute to guarantee its most potent form for an optimally effective product. Contraction lines, forehead wrinkles, crow's feet wrinkles and nasolabial folds are all visibly corrected. 

    After 14 days, wrinkles are significantly reduced:

    • - 8.6% expression wrinkles2
    • - 8.6% nasolabial folds2
    • - 11.4% forehead wrinkles2

    Skin texture and radiance are also visibly improved:

    • + 22.3% radiance3
    • + 18.6% improved skin texture3


    (1) Real-life test, 72 consumers over 14 days
    (2) Clinical study on 15 subjects, 2 applications per day for 14 days, average % of reduction.
    (3) Clinical study on 40 subjects, 2 applications per day for 14 days.

    Discover the Tightening Serum

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    CLINICALLY PROVEN RESULTS IN RECORD TIME⁵

    (5) Clinical study on 40 subjects, 2 applications per day for 14 days.

    1. Skin looks 2 years younger

      after just 14 days of use*

    2. 5 signs of ageing corrected

      in 14 days: wrinkles, volume, firmness, radiance, complexion**

    3. Immediate smoothing effect***

    * Evaluation after 2 weeks of twice-daily application based on clinical evaluation using a database, on 15 subjects.
    ** Real-life test, 72 consumers after 14 days of product application.
    ***Real-life test on 72 consumers immediately after product application

    HYALURON ACTIV PROCEDURE - Micro-Lift Eye & Lip Cream

    With its high-precision tip, this treatment can be applied directly onto targeted areas such as the eye contour, lip contour, and specific wrinkles. Each application helps visibly firm facial contours and correct wrinkles, even deeper lines.

    Discover the Micro-Lift Cream & Lips

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    TARGETED APPLICATION FOR ENHANCED RESULTS

    1. -14,7%

      crow’s feet wrinkles*

    2. -10,9%

      lip contour wrinkles **

    3. +40%

      smoother skin*

    *Clinical study on 38 subjects, 2 applications per day for 2 months.
    **Clinical study on 39 subjects, 2 applications per day for 2 months.
    ***Clinical scoring on 44 subjects, 1 application per day for 2 months.

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    Don't wait any longer to embrace the latest innovations in Avène Dermo-Aesthetics.

    FREQUENTLY ASKED QUESTIONS ABOUT HYALURON ACTIV PROCEDURE RANGE

    Do you have a doubt ? We’re always here for you

    Based on a person’s date of birth, we can determine their chronological age. Simply corresponding to the number of years lived, this universal measurement is independent of the individual and their environment. But what about their biological age, do we truly know it?

    Biological age refers to the physiological state of the body. Reflecting the cumulative effects of lifestyle, genetics, and environmental factors, this multifactorial measure provides a much more accurate assessment of cellular vitality and function.

    Measuring biological aging and thus the skin’s true age is a key step in developing innovative skincare solutions backed by cutting-edge research and advanced technologies.

    Thanks to large-scale knowledge-based research and skin biopsies, Pierre Fabre R&D has been able to determine the biological age of a sample group.

    After two months of using the Lifting Cream, a 7-year improvement in biological age was demonstrated, restoring cellular function. The skin looks 7 years younger*

    *Pharmaco-clinical study, on 42 women, 1 application/day of the product for 2 months.

    Retinal is the direct precursor of retinoic acid, the most active form of vitamin A allowed in cosmetics. Retinal is 3x more effective than retinol*.

    *Ex-vivo test.

    Our 30+ years of experience with Retinal allow us to confidently confirm the safety of using this active ingredient during the day:Toxicology: Our in vitro data show no phototoxicity.

    • The toxicology department validates its daytime use.
    • Cosmetovigilance: With over 30 years of use, we have strong evidence of good tolerance.
    • Photostability: The active ingredient is photostable.

    Retinal has been shown to be a well-tolerated active ingredient. Our 30 years of experience in cosmetovigilance support its safety profile. Additionally, all products in the Hyaluron Activ Procedure range have been tested and approved for post-procedure tolerance (peeling, laser, injections).

    However, every skin is unique and may react differently. That’s why we recommend a gradual introduction. Start with one to two applications per week during the first two weeks, then gradually increase to once daily, preferably in the evening, depending on your skin’s tolerance.

    To maximize the effectiveness of our products, we use the highest concentration of Retinal: 0.1%. As a result, the Lifting Cream should be used only once a day.

    Retinal, the star active ingredient in the range, is naturally bright yellow.
    We have chosen not to add any colorants to our formulas in order to preserve the natural color of this ingredient.
    It may leave a residual tint on the skin or fabrics, which can be minimized by allowing the product to fully absorb and letting the skin dry completely.
    This residual color is easily removed with water.