Using a cutting-edge biotechnological process, Avène Dermatological Laboratories have succeeded in extracting D-Sensinose™, a post-biotic active ingredient capable of acting directly on sensory neurons to calm the skin and control its hyper-reactivity. This 3rd generation biotechnological active ingredient with outstanding properties marks a major advance for all hypersensitive skin types that need to reduce their reactivity.
Twenty years of research have enabled the Avène Dermatological Laboratories teams to fully grasp the potential of an extraordinary bacterium, Aquaphilus dolomiae, and to extract a biotechnological active ingredient with decisive benefits for hypersensitive skin.
Skin sensations originate in the sensory neurons at the periphery of the skin. The maladaptive response of hypersensitive skin (tingling, tightness, redness, discomfort) is largely due to a low tolerance threshold of these sensory neurons.
D-Sensinose™ acts directly on the transmission of the nervous message and modulates these perceptions, whatever the origin of the initial sensitivity (stress, pollution, cold, heat, etc.) and the type of skin sensation.
The skin is immediately soothed. Hypersensitivity is under control.
Hypersensitive, reactive, intolerant or allergy-prone skin...
a reality that is difficult to live with on a daily basis.
Tolérance CONTROLis the new solution for any skin type that needs immediate hydration and soothing.
These innovative skin care products have been designed to calm, moisturise and restore all hypersensitive skin, in adults and children alike.
At the heart of its effectiveness? The new ultra-calming post-biotic active ingredient D-Sensinose™, incorporated in a biomimetic "Skin affinity" formula that perfectly mimics the natural composition of the skin barrier for optimal tolerance. This optimises the effectiveness of D-Sensinose™: the right dose in the right place.
A bio-adaptable formula for immediate and lasting effectiveness(1): The skin is calmed in 30 seconds(2) and moisturized for 24 hours(3). The skin barrier is restored within 48 hours(4).
Your skin can no longer tolerate anything and reminds you of that on a daily basis. With Tolerance CONTROL skincare products, you can choose between two textures to soothe, moisturize and restore your hypersensitive skin.
*Patent pending
(1) Sensitive scale. Results at T0 on 25 subjects.
(2)User satisfaction, 25 subjects, 3 months, 2 applications per day.
(3) HI kinetics, 26 subjects
(4) Ex-vivo test on epidermis grown in reduced water conditions.
