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Cleanance

Comedomed Localized drying emulsion

Drying, anti-blemish Permanent

  • Localised and rapid action.
  • Comedomed Localized drying emulsion
  • Comedomed Localized drying emulsion
  • Anti-imperfections
    • Comedomed Localized drying emulsion
    • Comedomed Localized drying emulsion
    • Comedomed Localized drying emulsion
    • Comedomed Localized drying emulsion

      Cleanance

      Comedomed Localized drying emulsion

      Dries out imperfections - Reduces the appearance of residual marks Permanent

      An intensive ''SOS'' treatment that reduces the appearance of localized imperfections from 1 day¹ and of associated residual marks.

      • Localised and rapid action.
      • Drying, anti-blemish
      Tube

      Usable by Teenagers - Adults

      Skin type Acne-prone skin

      Need Anti-imperfections

      Made in France

      The Cleanance Comedomed Localized drying emulsion is an ''SOS'' skincare for dry skin that reduces the appearance of localized imperfections and limits the look of residual marks. Visible effect from the first day of application*. This skincare combines a unique complex of dermatological key ingredients with formidable properties while ensuring good tolerance: Comedoclastin™ at a dosage of 7% (stabilized milk thistle extract with patented properties), retinaldehyde at 0.1% (cosmetic precursor of vitamin A) and glycolic acid at 6%. The recipe for success! Easy to dose and apply thanks to its targeted cannula tip, this ultra-light emulsion penetrates the skin quickly.

      A few words from our expert

      An ''SOS'' skincare that reduces the appearance of localized imperfections from the first day of application* and limits the look of marks.

      Benefit

      Reduces the appearance of spots from the first day* while limiting the appearance of marks.

      Benefits

      • REDUCES the appearance of spots.
      • DRIES OUT localized blemishes.
      • LIMITS the appearance of residual marks.

      Texture benefit

      A gel-cream texture that is quickly absorbed.

      Product scent

      Fragrance-free

      Packaging that does not contain recycled material
      Not recyclable packaging

      2025-09-22

      * Decrease in the clinical scoring of volume and redness assessed after 1 day of application, 3 times per day, 40 subjects.

      *Decrease in the clinical scoring of volume and redness assessed after 1 day of application, 3 times per day, 40 subjects.

      Environmental impact

      Formula

      Formula rating : D

      Packaging

      Packaging rating : D

      Manufacturing

      Manufacturing rating : C

      Made in a factory certified for the environment*
      *According to ISO 14001 standard and/or 50001

      Transportation

      Transportation rating : B

      Average CO2 impact of the transport of raw materials
      Product manufactured and packaged on sites located less than 1000km from each other

      Societal impact

      Societal impact

      Societal impact rating : A

      Product manufactured and packaged in a factory with high social compliance
      Avène is a brand of the Pierre Fabre Group, certified at the highest Exemplary level of AFNOR Certification’s ‘Committed to CSR’ and ‘Responsibility Europe’ labels, thus consolidating a long-standing commitment to sustainable development.
      Does not contain raw materials of animal origin

      Our commitments

      Application

      Frequency of use

      2 to 3 times a day

      Apply a thin layer 2 to 3 times a day** to the blemish until it disappears completely.

      ** Effectiveness evaluated following 3 applications per day.

      Ingredients

      AVENE THERMAL SPRING WATER (AVENE AQUA). CAPRYLIC/CAPRIC TRIGLYCERIDE. ISODODECANE. GLYCOLIC ACID. ISOPROPYL ALCOHOL. PEG-6. GLYCERIN. WATER (AQUA). HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER. SODIUM HYDROXIDE. GLYCERYL STEARATE. PEG-100 STEARATE. POLYMETHYL METHACRYLATE. ARACHIDYL ALCOHOL. ARACHIDYL GLUCOSIDE. BEHENYL ALCOHOL. HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL (HELIANTHUS ANNUUS SEED OIL). POLYSORBATE 60. RED 33 (CI 17200). RETINAL. SILYBUM MARIANUM FRUIT EXTRACT. SORBITAN ISOSTEARATE. TOCOPHEROL

      The consumer is advised to systematically check the composition of the product before purchasing it.

      Retinaldehyde

      Retinaldehyde

      Direct precursor of retinoic acid, leading dermatological active ingredient. Reduces the appearance of residual marks and decreases their intensity by reducing hyperpigmentation and inducing the production of collagen and elastin.
      Comedoclastin™

      Comedoclastin™

      Plant-based key ingredient with patented properties from Pierre Fabre Research. Milk thistle extract has a powerful effect to reduce the appearance of imperfections. Fragrance-free, alcohol-free. The smell of the product is due to the strong presence of the active ingredient Comedoclastin™ in the product. The smell evaporates upon application.

      Results

      • Reduces the appearance of spots from the first day of application¹
      • After 2 days, 56% of the subjects in the treated group observed an improvement vs. 19% in the untreated group²
      • 87% of the subjects considered the product to be effective in limiting the appearance of residual marks³

        ¹ Decrease in the clinical scoring of volume and redness assessed after 1 day of application, 3 times per day, 40 subjects.
        ² Overall development of acne. % of subjects' skin improved after 2 days of application. Clinical study conducted on 18 subjects (aged 18 to 31). 3 applications per day on one half of the face.
        ³ Self-evaluation after 14 days. Using the Cleanance Comedomed Spot Treatment 3 times a day. 40 subjects.

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