Comedoclastin^TM

Comedoclastin^TM, a new ingredient with patented properties derived from Pierre Fabre's expertise

After 8 years of research and development to extract the most active component of the plant, Avene Dermatological Laboratories have produced Comedoclastin^TM from the seeds of Milk Thistle (Sylibum marianium L.). Pierre Fabre Botanical Expertise has obtained the active molecules and stabilised them to obtain a unique concentrate, an oil rich in active ingredients extracted from cold-pressed seeds in our ISO9100 certified factory in Gaillac, which guarantees traceability, safety and control of the manufacturing process. 

Predominantly grown in France in a short supply chain within a non-destructive industry, milk thistle extract meets the four founding pillars of the Pierre Fabre Botanical Expertise approach, a certified responsible development approach that consists of innovating through nature: fighting against the depletion of plant resources and contributing to their preservation, while guaranteeing the extreme quality of active plant ingredients, the security of supplies and respecting our partners.

And in a circular economy context, the residual oil of milk thistle obtained after extraction is also recovered.

Comedoclastin^TM is an effective part of our Cleanance Comedomed skin care range.

We have applied the effectiveness of our star ingredient Comedoclastin^TMto our entireCleanance Comedomedskin care range to treat the problem of oily or acne-prone skin: hyperseborrhea, i.e. the overproduction of sebum by the sebaceous glands, in two ways:

• In a hyper-concentrated form, with a 25% concentration of Cleanance Comedomed Anti-Blemish Concentrate, a treatment that reduces pimples and blackheads while limiting their recurrence to stop the vicious circle of pimples and leave your skin clear. 
• Combined with other ingredients across other products in the range such as Cleanance Gel, a mattifying gel cleanser that removes oil and impurities for perfectly cleansed and matte skin.